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However, a 2025 study in the Journal of the Endocrine Society found no confirmed association between tirzepatide and medullary thyroid cancer in humans

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Loss of facial volume and stretch in the face also accentuates wrinkles and lines

How it interacts with metoprolol: Metoprolol, as a beta-blocker, can block some of the effects of epinephrine, especially on the heart and blood vessels

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