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Longer trials without measurable results may simply waste time and money
Lancet Diabetes Endocrinol 2019 May

2024;16:e66280

Discussion In this study, we show that replacement of the murine GLP-1R with human GLP-1R results in a similar metabolic phenotype

Although GLP-1 medications help with weight loss on their own, healthy eating and physical activity can maximize your results

In patients who are normotensive, an ACE inhibitor or ARB should be started at a low dose and progressively uptitrated to avoid precipitating symptomatic hypotension
