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doi: 10.3945/ajcn.110.001586 188 LigneauXMorissetSTardivel-LacombeJGbahouFGanellinCRStarkHet al

It is important to note that mild, transient elevations in liver enzymes during GLP-1 therapy initiation are uncommon but may occur

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A notable RCT is the pioglitazone in early PD trial, which failed to demonstrate the possibility of pioglitazone delaying disease progression in early-stage PD patients [38]

For example, a clinical trial involving semaglutide reported that participants with a baseline body mass index (BMI) over 35 kg/m lost an average of 15% of their body weight after 68 weeks, while those with lower baseline weights lost less in relative terms