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The key metric is not time elapsed but clinical response

The primary outcome of the study, as in the prior open clinical trial, 46 was the severity of PD motor symptoms by using the MDS-UPDRS part 3 in the Practically defined OFF medication state at the 60-week time-point

Focused ultrasound on the substantia nigra enables safe neurotensin-polyplex nanoparticle-mediated gene delivery to dopaminergic neurons intranasally and by blood circulation

Standard colonoscopy does not use intravenous contrast agents

Safety: GLP-1 injections do have potential side effects

Thats a conversation best had with a Canadian-licensed clinician who can weigh your specific circumstances and recommend an appropriate path forward