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Oral formulations might enable obesity treatment to move decisively into primary care, extending its reach well beyond todays specialist base and giving access to greater numbers of patients earlier in the course of the disease

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95% CI 0.83 to 0.99), although to a lesser degree than SGLT-2 inhibitors

The remaining data processing was performed using the cryoSPARC v2 workflow

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AOM semaglutide also showed its largest quarter-over-quarter percentage point increase since the start of the study period, a trend likely driven by approval of the oral formulation of Wegovy in late 2025