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Androgen replacement has been associated with reductions in pro-inflammatory cytokine production and modulation of immune cell activity [24,25,26], mechanisms that may indirectly influence skeletal muscle preservation

Acknowledgements This research was supported by the Chan Zuckerberg Biohub, a Stanford Diabetes Research Center (SDRC) Pilot grant and the Transdisciplinary Initiative Program (TIP) from the Stanford Maternal & Child Health Research Institute (MCHRI)

GLP-1 inhibits the secretion of glucagon which is responsible for the release of glucose into the blood stream from various body storage sites