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Proper dosing schedules become essential because higher doses lead to more frequent side effects such as gastrointestinal upset, and the side effects can be managed by using the minimum effective dose or slow titration (Figure 2)

Read the full study: Helen Michaela de Oliveira MS, Mariano Reynaldo Gallo Ruelas RD, Pandora Eloa Oliveira Fonseca MS, Camilo Andr Viana Diaz MS, Guilherme Oliveira de Paula MS, Pablo Ramon Fruett da Costa MD, Tariq Parker MD, PhD, Kristopher T

This tool evaluates key domains such as Selection, Comparability, and Exposure