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Yet, the greatest and most lasting results are achieved when medication is combined with positive lifestyle changes

However, extensive research has verified that GLP-1RAs exert anti-inflammatory actions in various tissues and organs by modulating inflammatory and immune responses (Fig
Moreover, efpeglenatide therapy reduced the risk of CV disease by about 27% compared to the placebo in the Effect of Efpeglenatide on Cardiovascular Outcomes (AMPLITUDE-O) study [51]

2013;304(2):F137F144

Wegovy, in May 2024, was approved by the F.D.A
Metab Clin Exp (2021) 127:154937