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however, some discontinuations were actually due to "perceived excessive weight loss," highlighting the potency of the drug

Incretin-based therapies: Facing the realities of benefits versus side effects

Especially at higher doses

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Patients and healthcare professionals should be aware of the following: Retatrutide cannot be legitimately prescribed by UK clinicians outside of a clinical trial setting Any product marketed or sold as retatrutide outside of a regulated trial is unlicensed and potentially unsafe The MHRA advises caution regarding unlicensed weight-loss medicines, which may be counterfeit or of unknown composition

When vomiting occurs, stomach acids enter the mouth and touch the teeth, which can ultimately lead to weakening of the enamel due to the low pH of the stomach acids