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11041106, Oct

Zheng et al., 2016

Safety and tolerability of glucagon-like peptide-1 receptor agonists utilizing data from the exenatide clinical trial development program

These benefits occur through blood pressure reduction (1-5.4 mmHg lower systolic blood pressure) 10 , improved vascular function, and direct effects on the heart

Much like the injection, the main side effects of the oral pill are transient gastrointestinal effects, for example, nausea and constipation, which affected 74 percent of the trial participants, according to the OASIS trial, which was published in The New England Journal of Medicine

An FDA decision could be as early as 2027 based on estimated trial completion dates
