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In head-to-head clinical trials, the tirzepatide group often showed greater weight reduction and better blood sugar control compared to the semaglutide group at the doses studied

Obesity is a chronic medical condition, similar to high blood pressure or high cholesterol, that often requires ongoing treatment

They could also help ease supply shortages of injectable medications by providing an alternative format

ACKNOWLEDGEMENTS The authors are honored to acknowledge their collaborators among the veterinary staff at Brown University and Rhode Island Hospital

doi: 10.1016/j.ejphar.2015.09.024 186 SonH.BanasrM.ChoiM.ChaeS

Fragment ion tolerance was set to 30 ppm and precursor tolerance to 20 ppm, with one tryptic terminus per peptide and one peptide per protein established as prerequisites identification, and with up to two variable modifications per peptide permitted