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Description
It differentially induces internalization of GIPR versus GLP-1R, with full internalization of GIPR but limited internalization of GLP-1R
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Individual results depend on starting weight, dosage, consistency, and lifestyle
doi: 10.2337/dc100704 54 WasadaTMcCorkleKHarrisVKawaiKHowardBUngerRH
Slows Gastric Emptying Food stays in your stomach longer, which can cause nausea and fullness
Retatrutide (Phase 2): A 48-week Phase 2 trial reported mean weight reductions of up to 24.2% from baseline at the highest dose
