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Tirzepatide, a coagonist of GIPR and GLP-1R, is characterized by greater efficacy in both glucose lowering and weight loss than can be achieved with current selective GLP-1RAs (16), while having a comparable adverse event profile
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75 Although animal studies suggest the potential use of DPP4 inhibitors for SSc treatment, further clinical trials are needed to explore their effects on SSc patients
Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial
