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Analysis of the Select trial data on 17,604 people found Wegovy protected against heart disease even before people had lost clinically meaningful amounts of weight (considered as less than 5%)

These medications help control blood sugar and support weight loss by: By acting on the pancreas and brains appetite centers, semaglutide can help reduce calorie intake and promote steady weight loss especially when paired with a healthy diet and exercise plan

Larger amounts wont speed up results, and they may cause digestive discomfort

The tradeoff is regulatory: compounded drugs are not FDA-approved 1 and should be discussed carefully with a provider

However, Wegovy 7.2mg, now approved in the UK since January 2026, has produced results comparable to Mounjaros highest dose, with 33.2% of participants achieving 25%+ weight loss

Blood services prioritise donor wellbeing , and individuals experiencing active side effects from Wegovy should wait until they feel well before attempting to donate