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WHO GLP-1 Treatments: The World Health Organization has issued new guidelines endorsing GLP-1 agonists as essential treatments for obesity, highlighting the urgent need for action against the rising global obesity epidemic affecting over one billion people and posing serious health risks.

Long-term adherence is essential to realizing the full therapeutic potential of GLP-1s, yet behavioral factors (such as reaching personal weight goals or perceived social stigma) and systemic issues (like high out-of-pocket costs and fragmented care) disproportionately affect obesity patients

When people stopped taking one of the new weight-loss jabs they regained around 60% of their lost weight.

Weight loss and persistence with liraglutide 3.0 mg by obesity class in the real-world effectiveness study in Canada

Here, we explored the signaling pathway involved in the anti-apoptotic effect of GLP-1, and investigated whether metformin had an anti-apoptotic effect on beta cells