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Reflections on the discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions

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A meta-analysis in 2023 examined 93 clinical trials from ClinicalTrials.gov that compared GLP-1RAs direct or indirect impact on DR with placebo, insulin, or oral antidiabetic medications ( A Swedish cohort study examined the impact of multiple GLP-1RAs on the incidence of DR in 2,390 diabetic patients

The 8mg dose provides 100% responder rate at the 5% weight loss threshold and 91% at the 10% threshold

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