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Adapted from DeFronzo R The imbalance between alpha and beta cells is a novel mechanism implicated in the pathogenesis of Type 2 DM described in the last few years

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The main topics addressed in this paper include the role of early and sustained glycemic control and use of SUs in T2D management, the properties of gliclazide MR in relation to its effectiveness and safety, the use of gliclazide therapy in special populations, and the place of SUs as a class and gliclazide MR specifically in the current T2D treatment algorithm.

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Not intended to diagnose, treat, cure, or prevent any disease
