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Once the five-year scheduled treatment period is completed and all the participants have stopped their study treatment, we will analyse the main results of the trial

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In a cohort study of individuals with T2D and metabolic-associated fatty liver cirrhosis (459 GLP-1RA users), GLP-1RA therapy was associated with reduced risks of hepatic decompensation, portal hypertension, hepatocellular carcinoma, and liver transplantation (111)

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In humans, cardiac GLP1R expression appears enriched in the sinoatrial node and conduction tissue rather than in working ventricular myocardium [16, 17]

Methods Data Source, Study Design and Eligibility Criteria This was a retrospective observational study (Fig