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Unlike AAV vectors, which provoke immunological responses after the second administration, LNPs are expected to allow repeated administrations 37,38
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In a rat model of SNL, intrathecal administration of exendin-4 significantly alleviated pain-induced hippocampal neuroinflammation and enhanced cognitive recovery [68]
Brain structural alterations in obese children with and without Prader-Willi syndrome

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Roos, E