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After 4 weeks this will increase to 5 mg once per week

About one-third of participants achieved 20% or greater weight loss, while some achieved less than 10%

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Taking two doses too close together (less than 72 hours apart) increases the risk of gastrointestinal side effects, including nausea, vomiting, and diarrhea, which are the most common adverse reactions associated with tirzepatide

13 This difference may be due to inadequate power in our study since we had LDL data in only a subset of subjects

Koralegedara IS, Warnasekara JN, Dayaratne KG, De Silva FN, Premadasa JK, Agampodi SB