soul trial oral semaglutide cardiovascular outcomes nejm 2025 results Forecasting Trial Milestones: A Predictive Analysis for Early Termination of the SOUL Study Novo Nordisk reports SOUL trial
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The excess risk of acute pancreatitis was more pronounced during the early phase of follow-up (first 6 months)

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The presence of concomitant hypertension in diabetics is a major driver of excess cardiovascular risk

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