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tirzepatide, or review the NIH / NIDDK overview of prescription weight-management medications and Mayo Clinics guide

A gradual transition is critical

Diabetes Res Clin Pract 139:239252

The dosing guide details all escalation options

After Dose Increases Headaches may resurface when moving from a lower dose (such as 0.25 mg) to a higher dose
For nausea management specifically, B6 remains the superior choice
