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WCDD301 does not affect the secretory function of cells over a range of concentrations (Figure 2, DF), and WCDD301 administration achieves euglycemia without clinical signs of illness, hepatotoxicity, or nephrotoxicity (Supplemental Table 2)

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Rare cases of shingles reported during GLP-1 use typically occurred in individuals with known risk factors (age, prior chickenpox) rather than forming a new pattern linked to the drug

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