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Description
Initial reports in animals showed that GLP-1 acutely increases blood pressure (BP) and heart rate (HR) in rats and mice, actions mediated through activation of the autonomic nervous system, including medullary catecholamine neurons, providing input to sympathetic preganglionic neurons (13)
Gudin B, Ladhari C, Robin P, Laroche ML, Babai S, Hillaire-Buys D, et al
And this supposedly makes sense because the manufacturer will not secure as much market share for their product when there are more therapeutic options being covered
doi: 10.1007/s40618-021-01635-z 35 AgarwalRFilippatosGPittBAnkerSDRossingPJosephAet al
It could take years of study and observation to fully understand the drugs long-term effects, both positive and negative
In clinical trials, Semaglutide has demonstrated an average weight loss of about 15%
