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Numerous studies have shown that high concentrations of FFA are noxious to -cells, and when infused in large amounts in humans and rodents, they produce suppression of insulin secretion (Hauke et al., 2018

The journey from discovery of the GLP-1 hormone to treatments for diabetes and then obesity was a long and stuttering one, spanning more than four decades and involving hundreds of researchers across academia and the pharmaceutical industry

Nat Rev Endocrinol 14 , 390403 (2018)

The PlexusDx Precision Peptide Genetic Test identifies variants in GLP1R, GIPR, FTO, and MC4R genes that predict appetite regulation, metabolism, and weight-regain risk

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Hero C, Rawshani A, Svensson A-M, et al

Simon MC, Strassburger K, Nowotny B, Kolb H, Nowotny P, Burkart V, et al
