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Thus, CBD activates PPAR receptors causing less expression of proinflammatory genes (Fig

Abbreviations used in this paper: ALI acute lung injury BALF bronchoalveolar lavage fluid cAMP cyclic adenosine monophosphate COPD chronic obstructive pulmonary disease FDA US Food and Drug Administration FEV1 forced expiratory volume in one second FVC forced vital capacity GLP-1 glucagon-like peptide-1 GLP-1R glucagon-like peptide-1 receptor ILC2 group 2 innate lymphoid cells IL interleukin LPS lipopolysaccharide NO nitric oxide OVA ovalbumin PKA protein kinase A RSV respiratory syncytial virus T2D type 2 diabetes mellitus Th2 T-helper type 2 TSLP thymic stromal lymphopoietin Footnotes Declaration of Interest: The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed Reviewer Disclosures: Peer reviewers on this manuscript have no relevant financial or other relationships to disclose

Lancet2006 Nov 11;368(9548):1696-705

But the trajectory matters more than today's number

Neural and psychological predictors of treatment response in irritable bowel syndrome patients with a 5-HT3 receptor antagonist: a pilot study

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