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doi: 10.1111/obr.12527 15 KillgoreWDWeberMSchwabZJKipmanMDelDonnoSRWebbCAet al

Tirzepatide mimics two hormones, GIP and GLP-1, which signal the brain that you are full and slow the rate of gastric emptying, which refers to how quickly a meal leaves the stomach and enters the small intestine

Without the medication, the hormonal environment actively promotes weight regain

A history of weight management attempts including diet, exercise, and any previous medications
BMI 35: Higher dosage (up to 15 mg) is often recommended for greater fat loss

Metabolic syndrome in patients with diabetes mellitus
