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Aims/hypothesis Unimolecular peptides targeting the receptors for glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and glucagon (GCG) have been shown to improve glycaemic management in both mice and humans

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Unlike traditional alcohol dependence medications, which often work by creating aversion or blocking euphoria after drinking, GLP-1 therapy works upstream reducing the desire before it takes hold

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In our December 2025 edition, we called it: 2026 would be the year of obesity pills.

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