dehydration on glp 1 a GLP-1, can feel like absolute death and here's why ๐ 1๏ธโฃ Slower gastric emptying GLP-1s already slow digestion. Add dehydration and food + meds just sit there longer, which GLP-1s and Kidney Function: Dehydration,
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Were looking forward to catching up with industry leaders, researchers, and sponsors to discuss how we can drive progress together

An AI study analyzing more than 400,000 Reddit posts identified patient-reported symptoms associated with GLP-1 medications that do not appear on drug labels.

The poll finds 12% of adults report having taken one of these GLP-1 drugs, which include Ozempic, Webovy and Mounjaro
The GLP-1 receptor agonist semaglutide reduces risks of kidney function loss, kidney failure, cardiovascular events, cardiovascular death and all-cause mortality in people with CKD and T2DM Ongoing clinical and mechanistic studies are expected to expand use of GLP-1 receptor agonists, GLP-1/GIP and other metabolic hormones for the treatment of CKD At the moment the most complete data is available for semaglutide from SUSTAIN-6 and FLOW trial which is the only trial with primary renal outcome in T2DM patients out of all GLP-1 RA Very good data for renal outcomes as secondary ones available for GLP-1 RAs dulaglutide and liraglutide and GLP-1/GIP RA tirzepatide, Very interesting and positive data from mechanistic REMODEL trial with semaglutide in T2DM patients presented but not yet published (reduced perirenal fat, rernal fibrosis and much more) Based on following excellent papers: #glp1 #gip #semaglutide #tirzepatide #liraglutide #dulaglutide #kidney #ckd #chronickidneydisease #cardiovascularcomplications

The magnitude of the benefits of GLP-1RA and SGLT-2 inhibitors on MACE are similar, ranging from 12 to 14% reduction of risk, but only GLP-1RA may reduce the risk of stroke

When compounded semaglutide and tirzepatide fail sterility and potency testing, and get distributed anyway, the implications extend far beyond one pharmacy.
