glp 1 antagonist drugs GLP-1 Agonists Examples: Which One Wins? Frontiers | Clinical perspectives on
Description
It is unique from the other GLP-1 medications because it is a twincretinit mimics both the incretin hormones as both a GLP-1 and a GIP receptor agonist

Nagashima et al

CRP, C-reactive protein

Because of this (long) half-life, semaglutide is usually given as a once-weekly injection, which helps maintain a steady level in your system over time

Other Safety Considerations Several additional safety topics are relevant to the clinical use of orforglipron: Gallbladder events: GLP-1 receptor agonists have been associated with increased rates of cholelithiasis and cholecystitis, likely mediated by rapid weight loss altering bile composition and gallbladder motility

doi: 10.2337/db15-0893
