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47 In our study, immunohistochemical staining revealed that GLP-1R is expressed in mouse CSMCs, suggesting that GLP-1 can directly influence CSMC function

Patients should be advised that these dietary and lifestyle approaches work synergistically and are most effective when implemented as part of a comprehensive, sustainable pattern rather than isolated interventions

Specifically, Frias et al

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But the truth is these medications arent for everyone, can be expensive, and require careful medical oversight