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6 Liraglutide should be used with caution in people with severe congestive heart failure, or a history of thyroid disease or pancreatitis

Full contour and comfort with vigorous exercise usually emerge over two to six months, once healing is stable

Instances of weight gain during treatment are more likely attributable to the individual factors outlined in earlier sections than to the drug itself

The simple answer

The dominant reasons, documented across multiple 2025 real-world studies, are: cost and insurance denials (47.6% of discontinuations), intolerance of GI side effects (14.6%), and supply shortages (11.8%)

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