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In recent years, considerable attention has been devoted to studying the post-prandial response after bariatric surgery [3, 6, 7]

[1] [3] The 3 mg dose is used only as a starting dose to improve gastrointestinal tolerability and is not intended for maintenance therapy

First, GLP-1RA can activate the first messenger adenylate cyclase (AC) after binding to the receptor, which stimulates an increase in the secretion level of the intracellular second messenger cyclic adenosine phosphate (cAMP) and subsequently activates the intracellular secondary messenger protein kinase A (PKA) ( Figure 1 For example, after GLP-1RA stimulates the activation of AC (5355) to promote learning and memory