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Surprisingly, degradation of platypus and echidna GLP-1 was observed when incubated in platypus and echidna sera (Fig

Clinicians should screen for eating disorders prior to prescribing, discuss risks transparently, monitor patients closely, and prioritize long-term recovery over short-term weight outcomes

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Other mutations, Y69 ECD A, Y88 ECD A, and L89 ECD A, have caused catastrophic effects on the ability of the receptor to be detected in binding or signaling assays (Underwood et al., 2010)

(3) high safety and efficacy, basically equal to antibody drugs

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