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The AGE/RAGE signaling further amplifies the expression of cytokines and intensifies oxidative damage by activating NADPH oxidase (NOX) (Rezaeinezhad et al., 2021

, Jeppesen, J

The pathophysiology of MASLD/MASH encompasses complex interactions among genetic background, impaired insulin signaling, hepatic lipid accumulation, inflammatory cascades, and progressive fibrosis

Understanding Tirzepatide and Temperature Sensitivity Tirzepatide is a dual-action medication known as a GLP-1 and GIP receptor agonist