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Licensed from Lilly in 2019, Xinermei, also known as mazdutide, is priced at 2,920 yuan ($411) per month for the highest dosage, compared with about $400 for Wegovy and $900 for Mounjaro

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104:3077-3087 [PubMed: 30835263] 225

Nonetheless, the present study demonstrates that therapeutic inertia represents a significant issue, particularly among non-GLP-1RA users

Dehydration is a related concern, as both reduced fluid intake (due to appetite suppression) and increased fluid losses (from gastrointestinal side effects) can contribute to volume depletion

The preclinical evidence on the benefits of GLP1R in other types of cancer is sparse and mixed