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Approved 20 years ago as a treatment for diabetes, GLP-1 drugs have been found also to help patients significantly reduce weight

Recent Findings Newer generation GLP-1 based therapies have become more effective for the treatment of overweight and obesity, with data supporting tirzepatide as the most effective, followed by semaglutide and then liraglutide

These nutritional supplements could help offset some of the downsides.

And the 5-year data depends entirely on who you are, why you're taking it, and how fast you're losing weight

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