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Fras JP, Davies MJ, Rosenstock J, Prez Manghi FC, Fernndez Land L, Bergman BK, Liu B, Cui X, Brown K, for the SURPASS-2 Investigators

The reality across all these products is that the skin barrier effectively blocks peptides larger than 500 Daltons from absorption, making their weight loss claims scientifically implausible

Although the difference in the incidence of MACE between GLP-1 RA and comparators failed to show statistical significance (Mantel-Haenzel odds ratio, 0.78

If these data were unavailable, the brand name of the most recent GLP-1 RA prescription fill was used to infer the indication

The magnitude of body weight loss for liraglutide-treated rats was stronger than sCT- and vehicle-treated animals

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