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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Kadouh H., Chedid V., Halawi H., Burton D.D., Clark M.M., Khemani D., Vella A., Acosta A., Camilleri M

Clinical trials did not identify back pain occurring at significantly higher rates compared to placebo

135,136 Based on these findings, CYP- and transporter-mediated DDIs involving peptide drugs are not negligible and should be carefully evaluated

E., Knudsen L

Similar results of gliosis reduction have been shown after subcutaneous administration of exendin-4 to mice on HFDs [41]

Indeed, -arrestin-1 knockdown attenuated GLP-1 signaling and impaired both glucose- and GLP-1induced insulin secretion in INS-1 pancreatic beta cells (48)
