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These typically occur during early treatment as the body adjusts to the medication
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While prescribed PERT products are regulated as medicines, most over-the-counter enzyme supplements are regulated as food supplements in the UK, with less stringent quality controls

This represents a key mechanism by which tirzepatide produces greater weight loss than diet alone despite similar caloric restriction
Side effects can last more than a week after the last injection Side effects include nausea, heartburn, vomiting and diarrhea

A loss of 24 pounds in the first month is common for many patients, though individual variation is significant
