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Significance statement ![Figure][1] ### Competing Interest Statement The authors have declared no competing interest

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Pfizer plans to conduct dose optimization studies in the second half of 2024 evaluating multiple doses of the preferred modified release formulation to inform the registration enabling studies

The latest South Park special, called The End of Obesity, now streaming on Paramount+, takes aim at the Ozempic craze and brutally targets the singer/rapper, Lizzo.