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The timing of FDA approvals reflects regulatory confidence in each agent independently

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Branded partnerships, alternative weight-loss therapies, and expansion in core categories can offset some pressure, but investors will demand clearer evidence of durable unit economics without regulatory gray zones driving acquisition

Despite having minimal effects on body weight, treatment with -MSTN/-ActA alone also showed beneficial shifts in the lean/fat body composition in obese mice as previously shown in non-obese mice, NHPs, and humans (Fig