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Patients with type 2 diabetes who are prescribed liraglutide have a 179% higher likelihood of developing non-arteritic anterior ischemic optic neuropathy (NAION), while those prescribed insulin have an 86% greater likelihood compared to patients who were prescribed other diabetes medications

In late April 2025, the FDA issued a key update regarding the use of compounded GLP-1 receptor agonists like semaglutide and tirzepatide

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