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Description
Restless legs syndrome (RLS) is a disorder that causes an overwhelming urge to move ones legs
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Combining GLP-1 medications like semaglutide with antidepressants such as bupropion requires medical oversight

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We also discuss combination therapies and strategies to mitigate muscle mass loss during treatment and calls for targeted research, improved clinical education, and policy reforms to optimize the translational potential of GLP-1R agonists in both individualized care and population health
