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Int J Obes (Lond) 2024;48(8):11181125
The pharmacologic effects of GLP-1 are noted in the next figure
As many as two-thirds of people using a GLP-1 to lose weight stop taking the drug within a year, citing unpleasant side effects (diarrhea, constipation, nausea and vomiting) and the relatively high cost of the medication
Third, GLP-1 RAs potentially affect coronary plaque characteristics
You have not needed any pain medication
This dual effect could explain why GLP-1 analogues, unlike dexamethasone, improve both synovitis and fibrosis in preclinical models
