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Rita Kathawa, MD , double board-certified in Internal Medicine and Obesity Medicine

~ AlphaMD You've been using Ozempic for a few months now, the scale is finally moving in the right direction, but something feels off

If weight loss has slowed or plateaued on one medication, a prescriber may recommend trying another most often a move from semaglutide (Wegovy) to tirzepatide (Mounjaro)

This phenomenonsometimes called tolerance or adaptationis real, common, and manageable

Set up in 1987 in San Diego, Amylin was a small biotechnology company already developing another diabetic drug and agreed to take the gamble with Raufman and Eng's peptide

Patients should be counseled on maintaining adequate hydration and balanced nutrition despite reduced appetite