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The hormonal changes are not your fault and not simply a matter of eating less or exercising more

The trials employed randomised, placebo-controlled designs with single ascending dose (SAD) and multiple ascending dose (MAD) protocols

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According to the famous Wisconsin Cohort Sleep Study , a 10% weight gain resulted in a 32% increase in participants AHI scores, plus they were also 6 times more likely to develop moderate to severe OSA
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