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Participants in the SGLT2i group demonstrated improvement in renal function with an increase in mean eGFR over the 5-year follow-up period (+3.5 ml/min per 1.73 m 2 ), compared with an overall reduction in eGFR in the GLP-1 RA cohort (7.2 ml/min per 1.73 m 2 )

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Negative energy balance and weight loss can activate the hypothalamic-pituitary-adrenal axis, elevating cortisol levels

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Exendin(939) itself did not affect glucagon secretion at 1 mmol/l glucose (Fig

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