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When lifestyle modifications prove insufficient, several FDA-approved pharmacologic options, such as orlistat, phentermine-topiramate, naltrexone-bupropion, liraglutide, semaglutide, and tirzepatide, can be considered

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Yet the identity of the downstream signalling events mediated by these peptides remain to be elucidated

These efforts aim to establish novel roles for GLP-1RAs in cancer prevention
