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Setting Realistic Weight Loss Expectations The Phase 3 ATTAIN-1 trial showed mean weight loss of approximately 11% at 72 weeks for the orforglipron 36 mg group

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Dietary Adjustments Simple dietary changes can significantly reduce digestive side effects: Eat smaller meals: Large meals can worsen nausea and stomach discomfort Choose bland foods: Avoid spicy, fatty, or heavily seasoned foods initially Stay hydrated: Drink plenty of water, especially if you experience vomiting or diarrhea Eat slowly: Take time with meals to aid digestion Timing Considerations The timing of your injection can affect side effects

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Prioritize protein Protein helps stimulate GLP-1 secretion

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